夏效东

夏效东，男，1981年8月出生，博士，西北农林科技大学食品科学与技术学院教授，博士生导师。兼任西北农林科技大学中美食品安全联合研究中心副主任。美国食品技术协会会员及美国微生物学会会员。陕西省青年科技新星及教育部新世纪优秀人才计划入选者。

一、学习情况

学士 合肥工业大学食品科学与工程专业，合肥，中国

硕士 中山大学营养与食品卫生专业，广州，中国

博士 美国马里兰大学，马里兰，美国

 二、工作简历

        2010.09－至今  西北农林科技大学食品科学与工程学院  教授；

     2014.11－至今  西北农林科技大学中美食品安全联合研究中心  副主任；

     2016.03－2017.03  哈佛大学医学院  访问学者

三、研究领域或方向

食源性致病微生物的分子流行病学、致病机制以及应激机制；

天然活性物质的营养及抗菌功能

四、开设课程

承担本科生“食品安全风险分析与管理”及研究生“专业外语”等课程。

五、取得的研究成果和目前正在进行的科学研究工作情况

1. 获得省部级科技成果奖

1) 2013年获陕西省青年科技新星

2) 2013年获教育部新世纪优秀人才

2. 主持研究课题及经费到位情况

1) 陕西省科学技术研究发展计划青年科技新星项目-石榴皮提取物抗沙门氏菌感染的效应及机制研究(项目编号2013KJXX-16)，到位经费20万；

2) 十二五国家科技支撑计划子课题-功能因子关键功能特征体系研究与构建(项目编号2012BAH30F03)，到位经费25万；

3) 十二五国家科技支撑计划子课题-猕猴桃产品食源性致病菌全产业链识别、溯源与控制技术研究(项目编号2012BAK17B06)，到位经费15万；

4) 国家自然科学基金-石榴皮单宁对单核细胞增生李斯特菌的抑制机理及对其致病性的影响(项目批准号31101347)，到位经费24万元；

3. 以第一作者或通讯作者发表SCI/EI论文情况（2011-2016）

1) Shi C, Xia X*, Song K, Zhang X, Sun Y, Sui Y, Chen Y, Jia Z, Sun H, Sun Z. Antimicrobial Activity and Possible Mechanism of Action of Citral against Cronobacter sakazakii. [J]. PLoS One. 2016 11(7):e0159006. (SCI).

2) Han QA, Xia X*, Yan C, Wang L, Li G, Xu Y. Urolithin A attenuates ox-LDL induced endothelial dysfunction partly by modulating microRNA-27 and ERK/PPAR-γ pathway. [J]. Mol Nutr Food Res. 2016 doi: 10.1002/mnfr.201500827. (SCI).

3) Shi C, Xia X*, Sun Y., Zheng Z., Zhang X., Song K., Jia Z., Chen Y., Yang M., Liu X., Dong R. Antimicrobial activity of syringic acid against Cronobacter sakazakii and its effect on cell membrane. [J]. Food Chemistry, 2016, 197(Pt A):100-6. (SCI).

4) Shi C^#, Sun Y^#, Xia X*, Zhang X., Zheng Z., Yang M., Ben H., Song K., Cao Y., Chen Y., Liu X., Dong R. Antimicrobial effect of lipoic acid against Cronobacter sakazakii. [J]. Food Control, 2016, 59:352-358. (SCI).

5) Zhang Y, Xia X*, Qiao H., Chen C., Wang Z. Determination of nitrofurans metabolites residues in aquatic products by ultra-performance liquid chromatography-tandem mass spectrometry. [J]. Food Chemistry, 2016, 192:612-7. (SCI).

6) Yang Q, Xia X*, Wang L., Gao J., Liu X., Feng Y., Wu Q., Baloch A, Cui L*. Tannin-Rich Fraction from Pomegranate Rind Inhibits Quorum Sensing in Chromobacterium violaceum and Biofilm Formation in Escherichia coli. [J]. Foodborne Pathogens and Disease, 2015, 13(1). (SCI).

7) Feng Y, Xia X*,Yang Q., Wang L., Li G., Lv X., Han Q., Liu X. Survey of Microbial Contamination and Characterization of Escherichia coli in Kiwifruit Orchards in Shaanxi, China, 2013. [J]. Foodborne Pathogens and Disease, 2015, 12(10). (SCI).

8) Shi C, Xia X*, Jia Z., Chen Y., Yang M., Liu X., Sun Y., Zheng Z., Zhang X., Song K.,Cui L*, Baloch AB. Inactivation of Cronobacter sakazakii in reconstituted infant formula by combination of thymoquinone and mild heat. [J]. Journal of Applied Microbiology, 2015, 119(6):1700-1706. (SCI).

9) Peng X，Xia X*, Yang J.,Cui P.,Chen F.,Fu Y.,Hu Y.,Zhang Q. Influence of allicin on quality and volatile compounds of fresh-cut stem lettuce during cold storage. [J]. LWT-Food Science and Technology, 2015, 60(1):300-307. (SCI).

10) Li G，Xia X*, Feng Y., Xu Y., Wu Q., Han Q., Liang X., Yang B., Wang X. The anti-infective activity of punicalagin against Salmonella enterica subsp. enterica serovar typhimurium in mice. [J]. Food & Function, 2015, 6(7):2357-2364. (SCI).

11) Baloch. A, Xia X*, Sheikh S. Proximate and Mineral Compositions of Dried Cauliflower (Brassica Oleracea L.) Grown In Sindh, Pakistan. [J]. Journal of Food and Nutrition Research, 2015, 3(3):213-219. (SCI).

12) Xi M, Xia X*, Wu Q, Wang X, Yang B, Li D. Characterization of Extended-Spectrum β-Lactamase-Producing Escherichia coli Strains Isolated from Retail Foods in Shaanxi Province, China. [J]. Journal of Food Protection, 2015, 78(5):1018-23. (SCI).

13) Xi M, Xia X*, Feng, Y., Li, Q., Yang, Q., Zhang, B., Li, G., Shi, C. Prevalence, distribution, and diversity of Escherichia coli in plants manufacturing goat milk powder in Shaanxi, China. [J]. Journal of Dairy Science, 2015, 98(4):2260-7. (SCI).

14) Xu, Y, Xia X*, Li, G., Zhang, B., Wu, Q., Wang, X. Tannin-rich pomegranate rind extracts reduce adhesion to and invasion of Caco-2 Cells by Listeria monocytogenes and decrease its expression of virulence genes. [J]. Journal of Food Protection, 2015, 78(1):128-133. (SCI).

15) Zhang, B, Xia X*, Peng, X* , Li, G., Xu, Y, Wang, Q. Oxidative stress is involved in Patulin induced apoptosis in HEK293 cells. [J]. Toxicon, 2015, 94:1-7. (SCI).

16) Feng, Y, Xia X*, Li, G., Lv, X., Xu, Y., Wu, Q., Shi, C., Li, Q., Yang, B., Wang, X., Xi, M. Prevalence, distribution, and diversity of Escherichia coli, Staphylococcus aureus, and Salmonella in kiwifruit orchards and processing plants. [J]. Foodborne Pathogens and Disease, 2014, 11(10):782-790. (SCI).

17) Li, G, Xia X*, Xu, Y., Wang, X., Zhang, B., Shi, C., Zhang, W. Tannin-rich fraction from pomegranate rind damages membrane of Listeria monocytogenes. [J]. Foodborne Pathogens and Disease, 2014, 11(4):313-319. (SCI).

18) Li, G, Xia X*, Yan, C., Xu, Y., Feng, Y., Wu, Q., Lv, X., Yang, B., Wang, X. Punicalagin inhibits Salmonella virulence factors and has anti-quorum-sensing potential. [J]. Applied and Environmental Microbiology, 2014, 80(19):6204-11. (SCI).

19) Wang, X, Xia X*, Li, G, Yang, B., Xi, M., Meng, J. Antimicrobial susceptibility and molecular typing of methicillin-resistant Staphylococcus aureus in retail foods in Shaanxi, China. [J]. Foodborne Pathogens and Disease, 2014, 11(4):281-286. (SCI).

20) Wu, Q, Xia X*, Xi, M., Lv, X., Xu, Y., Feng, Y., Li, Q., Yang, Q. Presence and antimicrobial susceptibility of Escherichia coli recovered from retail chicken in China. [J]. Journal of Food Protection, 2014, 77(10):1773-1777. (SCI).

21) Yang B, Xia X*, Wang Q., Cui S., Wang Y, Shi C, Xi M., Wang X., Shi X., Wang D., Zhang Z., Meng J. Characterization of extended-spectrum beta-lactamases-producing Salmonella strains isolated from retail foods in Shaanxi and Henan Province, China. [J]. Food Microbiology, 2014, 42(12):14-18. (SCI).

22) Li, G, Xia X*, Antimicrobial effect and mode of action of chlorogenic acid on Staphylococcus aureus. [J]. European Food Research and Technology, 2014, 238(4):589-596. (SCI).

23) Peng X, Xia X*, Li R., Zou R., Chen J., Zhang Q, Cui P., Chen F., Fu Y. Yang J. Allicin Inhibits Microbial Growth and Oxidative Browning of Fresh-cut Lettuce (Lactuca Sativa) During Refrigerated Storage. [J]. Food and Bioprocess Technology, 2014, 7(6):1597-1605. (SCI).

24) Yang B, Xia X*, Qiao L., Zhang X., Cui Y. Cui S., Wang X., Meng J., Ge W., Shi X., Wang D., Meng J. Serotyping, Antimicrobial Susceptibility, Pulse Field Gel Electrophoresis Analysis of Salmonella Isolates from Retail Foods in Henan Province, China. [J]. Food Control, 2013, 32(1):228-235. (SCI).

25) Wang X, Xia X*, Tao X., Yang B., Xi M., Meng J., Zhang J., Xu B. Staphylococcus aureus and methicillin-resistant Staphylococcus aureus in retail raw chicken in China. [J]. Food Control, 2013, 29(1):103-106. (SCI).

26) Zhang, W, Xia X*, Wang, X.*, Yang, B., Xi, M., Meng, J. Isolation and characterization of Listeria monocytogenes isolates from retail foods in Shaanxi Province, China. [J]. Foodborne Pathogens and Disease, 2013, 10(10):867-872. (SCI).

27) Wang X, Xia X*, Meng J., Zhang J., Zhou T., Zhang Y., Yang B., Xi M. Characterization of Staphylococcus aureus isolated from powdered infant formula milk and infant rice cereal in China. [J]. International Journal of Food Microbiology, 2012, 153(1-2):142-7. (SCI).

28) Wang X, Xia X*, Meng J., Zhou T., Zhang Y., Yang B., Xi M., Sheng J., Zhi S. Antimicrobial susceptibility testing and genotypic characterization of Staphylococcus aureus from food and food animals. [J]. Foodborne Pathogens and Disease, 2012, 9(2):95-101. (SCI).

29) Xia X., Meng J.*, McDermott P. F., Zhao S. Escherichia coli from retail meats carry genes associated with uropathogenic E. coli, but are weakly invasive in human bladder cell culture. [J]. Journal of Applied Microbiology, 2011, 110(5):1166-76. (SCI).

30) Xia X., Meng J.*, Zhao S., Bodeis-Jones S., Gaines S. A., Ayers S. L., McDermott P. F. Identification and antimicrobial resistance of extraintestinal pathogenic Escherichia coli from retail meats. [J]. Journal of Food Protection, 2011, 74(1):2-166 , pp. 38-44(7). (SCI).

31) Xia X., Meng J.*, McDermott P. F., Ayers S. L., Blickenstaff K., Tran T.T., Abbott J., Zheng J, Zhao S. Presence and characterization of Shiga toxin-producing E. coli and other potentially diarrheagenic Escherichia coli in retail meats. [J]. Applied and Environmental Microbiology, 2010, 76(6):1709-1717. (SCI).

32) Xia X., Zhao S., Smith A., McEvoy J., Meng J., Bhagwat A. A.*. Characterization of Salmonella isolates from retail foods based on serotyping, pulse field gel electrophoresis, antibiotic resistance and other phenotypic properties. [J]. International Journal of Food Microbiology, 2008, 129(1):93-8 (SCI).

33) Xia X, Ling W.*, Ma J., Xia M., Hou M., Wang Q., Zhu H., Tang Z. An anthocyanin-rich extract from black rice enhances atherosclerotic plaque stabilization in apolipoprotein e-deficient mice. [J]. Journal of Nutrition, 2006, 136(8):2220-5. (SCI).

六、联系方式

通讯地址：陕西杨凌西农路22号 西北农林科技大学食品学院A524

邮编：712100

联系电话：029-87091391（办），13488187030（手机）

Email: xdxia@nwsuaf.edu.cn