王妍入

　　 　　

王妍入，女，博士，副教授，硕士生导师。食品科学与工程学院食品安全系主任。

一、 主要学习、工作经历

2014.07 -今，西北农林科技大学食品科学与工程学院，讲师/副教授

2008.09月-2014.06，中国农业科学院油料作物研究所，硕博连读,导师：李培武 院士

2011.09-2013.02，加州大学戴维斯分校，联合培养博士，导师：Bruce D. Hammock院士

2004.09-2008.06，河北农业大学，本科

二、研究领域

食品污染物快速检测技术研究。主要针对生物毒素、食源性致病菌等污染物开展纳米抗体等基因工程抗体研究及相应的快速检测与控制技术研究。

三、开设课程

承担本科生《食品分析与检验》、《食品仪器分析》、《食品大数据与追溯技术》、《农产品质量安全概论》等课程的教学工作。

四、主持的科研项目

（1）国家自然科学基金面上项目，32472439，2025.01-2028.12，主持。

（2）国家自然科学基金青年项目，31501560，2016.01-2018.12，主持。

（3）中国博士后科学基金面上项目，2019M653767，2023M742860，2019.01-2020.12，2024.01-2025.12，主持。

（4）陕西省重点研发计划项目，2020NY-188， 2023-YBNY-154，2020.01-2021.12，2023.01-2024.12，主持。

四、部分代表性学术论文

[13] Pengyu Chen, Qinkai Yang, Shurong Li, Xuan Liu, Bingzhi Li, Jiahao Zhang, Jianlong Wang, Xiaoyue Yue, and Yanru Wang*. Nanobody-Induced Aggregation of Gold Nanoparticles: A Mix-andRead Strategy for the Rapid Detection of Cronobacter sakazakii. Anal. Chem. 2024, 96, 17602−17611.

[12] Liao X, Zhang Y, Liang Y, Zhang L, Wang P, Wei J, Yin X, Wang J, Wang H, Wang Y*. Enhanced sandwich immunoassay based on bivalent nanobody as an efficient immobilization approach for foodborne pathogens detection. Anal Chim Acta. 2024, 1289:342209.

[11] Liao X, Wang J, Guo B, Bai M, Zhang Y, Yu G, Wang P, Wei J, Wang J, Yan X, Fan K, Wang Y*. Enhancing Nanobody Immunoassays through Ferritin Fusion: Construction of a Salmonella-Specific Fenobody for Improved Avidity and Sensitivity. J Agric Food Chem. 2024, 72(26):14967-14974.

[10] Yao Zhang, Xingrui Liao, Gege Yu, Juan Wei, Peng Wang, Yueqi Wang, Yinnan Jing, Jiamin Wang, Pengyu Chen, Jianlong Wang, Hong Wang*, and Yanru Wang*. Phage-Displayed Nanobody as a Sensitive Nanoprobe to Enhance Chemiluminescent Immunoassay for Cronobacter sakazakii Detection in Dairy Products. Analytical Chemistry 2023, 95, 36, 13698–13707.

[9] Gege Yu, Jiamin Wang, Yao Zhang, Haofen Wu, Yueqi Wang, Yan Cui, Yuefan Yang, Xiaoqian Tang, Qi Zhang, Jianlong Wang, Jing Sun, Ran Chen, Yanru Wang*, and Peiwu Li. Anti-Idiotypic Nanobody Alkaline Phosphatase Fusion Protein-Triggered On–Off–On Fluorescence Immunosensor for Aflatoxin in Cereals. Journal of Agricultural and Food Chemistry 2023 71 (45), 17391-1739

[8] Yueqi Wang, Liang Zhang, Peng Wang, Xingrui Liao, Yueyan Dai, Qingyan Yu, Gege Yu, Yao Zhang, Juan Wei, Yinnan Jing, Jiamin Wang, Pengyu Chen, Bing Guo, Jianlong Wang, and Yanru Wang*. Enhancing Oriented Immobilization Efficiency: A One-for-Two Organism-Bispecific Nanobody Scaffold for Highly Sensitive Detection of Foodborne Pathogens. Analytical Chemistry, 2023 95 (46), 17135-17142

[7] Mengfan Bai, Yueqi Wang,, Cui Zhang,, Ye Wang,, Juan Wei, Xingrui Liao,Jianlong Wang, Laura Anfossi, Yanru Wang*. Nanobody-based immunomagnetic separation platform for rapid isolation and detection of Salmonella enteritidis in food samples. Food Chemistry, 2023, 424, 136416.

[6] Peng Wang, Gege Yu, Juan Wei, Xingrui Liao, Yao Zhang, Yarong Ren, Cui Zhang, Yueqi Wang, Daohong Zhang, Jianlong Wang, Yanru Wang*. A single thiolated-phage displayed nanobody-based biosensor for label-free detection of foodborne pathogen. Journal of Hazardous Materials, 2022, 130157.

[5] Cui Zhang, Yueqi Wang, Zhaoli Liu, Mengfan Bai, Jianlong Wang, Yanru Wang*. Nanobody-based immunochromatographic biosensor for colorimetric and photothermal dual-mode detection of foodborne pathogens.  Sensors and Actuators B: Chemical , 2022, 369, 132371.

[4] Yarong Ren, Juan Wei, Ye Wang, Peng Wang, Yanwei Ji, Baoyuan Liu, Jianlong Wang, Gualberto González-Sapienza, Yanru Wang*. Development of a streptavidin-bridged enhanced sandwich ELISA based on self-paired nanobodies for monitoring multiplex Salmonella serogroups.  Analytica Chimica Acta , 2022, 1203, 339705.

[3]

Cui Zhang, Zhaoli Liu, Mengfan Bai, Ye Wang, Xingrui Liao, Yao Zhang, Peng Wang, Juan Wei, Haoyu Zhang, Jianlong Wang, Hong Wang, Yanru Wang*. An ultrasensitive sandwich chemiluminescent enzyme immunoassay based on phage-mediated double-nanobody for detection of Salmonella Typhimurium in food.  Sensors and Actuators B: Chemical , 2022, 352, 131058.

[2] Yarong Ren, Juan Wei, Yixin He, Ye Wang, Mengfan Bai, Cui Zhang, Linpin Luo, Jianlong Wang, Yanru Wang*. Ultrasensitive label-free immunochromatographic strip sensor for Salmonella determination based on salt-induced aggregated gold nanoparticles.  Food Chemistry , 2021, 343, 128518.

[1] Yixin He, Yarong Ren, Bing Guo, Yifei Yang, Yanwei Ji, Daohong Zhang, Jianlong Wang, Yanru Wang*, Hong Wang. Development of a specific nanobody and its application in rapid and selective determination of Salmonella enteritidis in milk.  Food Chemistry , 2020, 310, 125942.

五、获奖情况

（1）校青年教师讲课比赛一等奖（2022）

（2）校课程思政大练兵 思政教学能手（2023）

（3）西部联盟第一届课程思政案例大赛一等奖（2024）

（4）全国高等农林院校课程思政联盟优秀案例（2024）

（5）分析测试协会科技进步一等奖（2022，排名：6/9）

（6）陕西省高等学校科学技术研究优秀成果奖一等奖（2023，排名：3/10）

（7）中国分析测试协会科学技术二等奖（2023，排名3/10）

五、联系方式

通讯地址：陕西杨凌西农路22号西北农林科技大学食品学院

邮编：712100

Email: yanruwang22@163.com;yanruwang@nwafu.edu.cn