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单忠国

作者:         发布日期:2021-09-24     浏览次数:

     

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单忠国,男,1984年12月出生,辽宁大连人,博士,讲师

一、学习情况

2004.9-2008.6 辽宁师范大学,学士

2008.9-2011.6辽宁师范大学生命科学学院,硕士

2011.9-2015.12厦门大学环境与生态学院,博士

二、工作经历

2018.09-至今西北农林科技大学食品科学与工程学院,讲师

2017.03-2018.06 美国罗德岛大学药学院,博士后

2016.07-2017.03 中国科学院天津工业生物技术研究所,助理研究员

三、研究方向

天然活性物质功能开发和利用

四、研究成果

1. Shan Z G*, Wang M L, Zhao S Y, Xie X E, Yang D B, Liu W D**(2021). Cinnamaldehyde exerts prophylactic and therapeutic effects against  Vibrioanguillarum infection in Yesso scallop ( Patinopectenyessoensis ) by its directantimicrobial activity and positive effect on the innate immunity. Aquaculture, 538: 736588.

2. Shan Z G, Guan N, Yang Y P, Jin T, Xia X D*, Liu W D* (2021). Elucidation of the potential mechanism of punicalagin for conferringdisease resistance in Yesso scallops against  Vibrio anguillarum infection. Aquaculture,533: 736109.

3.Shan Z G, Yang Y P,Guan N, Xia X D*, Liu W D* (2020).NKL-24: A novel antimicrobial peptide derived from zebrafish NK-lysin thatinhibits bacterial growth and enhances resistance against  Vibrioparahaemolyticus  infection in Yesso scallop,  Patinopectenyessoensis.  Fish and Shellfish Immunology, 106: 431-440.

4. Shan Z G, Wei Z X and Shaikh Z A* (2018). Suppression of ferroportin expression by cadmium stimulates proliferation, EMT, and migration in triple-negative breast cancer cells. Toxicology and Applied Pharmacology, 356: 36-43.

5. Wei Z X, Shan Z G and Shaikh Z A* (2017). Epithelial-mesenchymal transition in breast epithelial cells treated with cadmium and the role of Snail. Toxicology and Applied Pharmacology, 344: 46-55.

6. Shan Z G, Zhu K X, Peng H, Chen B, Liu J, Chen F Y, Ma X W, Wang S P, Qiao K, Wang K J* (2016). The new antimicrobial peptide SpHyastatin from mud crab Scylla paramamosain with multiple antimicrobial mechanisms and high effect on bacterial infection. Frontiers in microbiology, 7: 1-14.

7. Shan Z G, Zhu K X, Chen F Y, Liu J, Peng H, Qiao K, Peng H and Wang K J* (2016). In vivo activity and the transcriptional regulatory mechanism of the antimicrobial peptide SpHyastatin in Scylla paramamosain. Fish & Shellfish Immunology, 59: 155-165.

8. Shan Z G, Li H J, Bao X B, He C B, Yu H N, Liu W D*, Hou L**, Zhu D, Sui L J, Zhu B, Li Y F. (2011). A selenium-dependent glutathione peroxidase in the Japanese scallop, Mizuhopectenyessoensis: cDNA cloning, promoter sequence analysis and mRNA expression. Comparative Biochemistry and Physiology Part B, 159(1):1-9.

五、科研项目

1.校企合作横向课题项目,K4030220475,2020-12至2022-12,主持。

2. 陕西省自然科学基金,青年项目,2020JQ-266,2020年-2021年,主持。

3.中国博士后科学基金,面上项目,2019M653766,2019-2021年,主持。

4. 西北农林科技大学博士科研启动项目,Z1090219012,2018年-2020年,主持。

六、授权发明专利

拟穴青蟹抗菌肽SpHyastatin的制备方法与应用专利。王克坚(导师),单忠国,彭会,刘杰,陈贝。CN104151414B

七、联系方式

通讯地址:陕西杨凌西农路22号西北农林科技大学食品科学与工程学院

邮政编码:712100

电子邮箱:shanzhongguo@nwsuaf.edu.cn


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