单忠国

　　 　　

单忠国，男，博士，副教授，博士生导师

一、学习/工作经历

2026.01-至今 西北农林科技大学食品科学与工程学院，副教授

2018.09-2025.12西北农林科技大学食品科学与工程学院，讲师

2017.03-2018.06 美国罗德岛大学药学院，博士后

2016.07-2017.03 中国科学院天津工业生物技术研究所，助理研究员

2011.9-2015.12厦门大学环境与生态学院，博士

2008.9-2011.6辽宁师范大学生命科学学院，硕士

2004.9-2008.6 辽宁师范大学，学士

二、研究领域

食品微生物安全控制，果蔬与肉类防腐保鲜。

三、研究成果

(1) Lei Yang, Xuanxuan Yuan, Dian Dai, Shuqiang Wang, Ying Wu, Haihua Wang*, Zhongguo Shan*, Biodegradable bioactive packing films based on zein and β-CD-MOFs for grapes preservation, International Journal of Biological Macromolecules, 2025, 322: 146924.

(2) Zhang Peiqing, Li Sihang, Xiao Fan, Xiao Yongfang, Zhang Yi, Shan Zhongguo *, Zhenyu Li*, Haihua Wang*, Fabrication of superhydrophobic PVDF composite membranes using modified ZIF-8 for efficient and stable membrane distillation: Mitigating fouling and wetting, Journal of Environmental Chemical Engineering, 2025, 13: 118618.

(3) Yang Dongbo, Yi Jing, Li Xiaoya, Li Xiaoya, Zhang Shuqi, Xiang Yiming, Liu Xingxing, Shan Zhongguo*, Wang Haihua*, Novel silver nanoparticles loaded Cu-based metal-organic framework as a promising antimicrobial material for controlling Escherichia coli O157:H7 in pork, Food Science and Human Wellness, 2025, 14(03): 914-924.

(4) Wu Ying, Shi Bei, Yang Lei, Wang Fei, Hou Lei, Shan Zhongguo *, Wang Haihua *, Cysteine-Functionalized Magnetic Manganese-Based MOF Composite for Enhanced Removal of Pb²⁺ from Water, Langmuir, 2025, 41: 10953-10964.

(5) Zhang Shuqi, Yi Jing, Zhang Zhilong, Yuan Xuanxuan, Shan Zhongguo*, Wang Haihua*, Preparation of zein active films with antimicrobial and antioxidant properties by incorporating gallic acid loaded γ-CD-MOF for pork preservation, Food Control, 2025, 167: 110822.

(6) Yi Jing, Zhang Shuqi, Zhang Zhilong, Yuan Xuanxuan, Shan Zhongguo*, Wang Haihua*, Development of multifunctional zein-based films engineered with gallic acid and Ag NPs loaded γ-CD-MOFs for pork preservation, Food Packaging and Shelf Life, 2024, 46: 101352.

(7) Zhang Shuqi, Yi Jing, Yuan Xuanxuan, Zhang Zhilong, Shan Zhongguo*, Wang Haihua*, Fabrication and characterization of carrageenan-based multifunctional films integrated with gallic acid@ZIF-8 for beef preservation, International Journal of Biological Macromolecules, 2024, 274: 133319.

(8) Shan Zhongguo, Wang Meilin, Zhao Shiyao, Xie Xiner, Yang Dongbo, Liu Weidong*, Cinnamaldehyde exerts prophylactic and therapeutic effects against Vibrio anguillarum infection in Yesso scallop (Patinopecten yessoensis) by its direct antimicrobial activity and positive effect on the innate immunity, Aquaculture, 2021, 538: 736588.

(9) Shan Zhongguo, Guan Ning, Yang Yanpeng, Jin Tong, Xia Xiaodong*, Liu Weidong*, Elucidation of the potential mechanism of punicalagin for conferring disease resistance in Yesso scallops against Vibrio anguillarum infection, Aquaculture, 2021, 533: 736109.

(10) Shan Zhongguo, Yang Yanpeng, Guan Ning, Xia Xiaodong*, Liu Weidong*, NKL-24: A novel antimicrobial peptide derived from zebrafish NK-lysin that inhibits bacterial growth and enhances resistance against Vibrio parahaemolyticus infection in Yesso scallop, Patinopecten yessoensis, Fish and Shellfish Immunology, 2020, 106: 431-440.

(11) Shan Zhongguo, Wei Zhengxi, Zahir A. Shaikh*, Suppression of ferroportin expression by cadmium stimulates proliferation, EMT, and migration in triple-negative breast cancer cells, Toxicology and Applied Pharmacology, 2018, 356: 36-43.

(12) Shan Zhongguo, Zhu Kexin, Chen Fangyi, Liu Jie, Chen Bei, Qiao Kun, Peng Hui, Wang Kejian *, In vivo activity and the transcriptional regulatory mechanism of the antimicrobial peptide SpHyastatin in Scylla paramamosain, Fish and Shellfish Immunology, 2016, 59: 155-165.

(13) Shan Zhongguo, Zhu Kexin, Peng Hui, Chen Bei, Liu Jie, Chen Fangyi, Ma Xiaowan, Wang Shuping, Qiao Kun, Wang Kejian *, The New Antimicrobial Peptide SpHyastatin from the Mud Crab Scylla paramamosain with Multiple Antimicrobial Mechanisms and High Effect on Bacterial Infection, Frontiers in Microbiology, 2016, 7: 1140.

四、科研项目

(1) 陕西省重点研发计划—一般项目，2026-2028，主持。

(2) 湄公河下游盆地可持续水稻生产的水-粮食-能源关系（LMB），2025-2026，主持。

(3) 横向课题，绿色多功能食品保鲜膜开发，2025-2026，主持。

(4) 横向课题，水产养殖动物石榴皮活性物质微胶囊饵料的开发，2025-2027，主持。

(5) 横向课题，食品微生物四川省重点实验室开放课题，2025-2027，主持。

(6) 横向课题，用于烟道气CO₂吸附的纸基MOF吸附剂开发，2025-2026，主持。

(7) 国家自然科学基金-地区科学基金项目（参与且有到位经费），2025-2028，参加。

(8) 陕西省自然科学基础研究—青年项目，2020-2021，主持。

(9) 中国博士后科学基金，面上项目，2019-2020，主持。

(10) 西北农林科技大学博士科研启动项目，2018-2020，主持。

五、教学与人才培养

主讲本科生《食品微生物学》、《食品微生物学实验》和《食源性致病菌新生研讨课》等课程。主持校级课程思政示范课程，荣获校级课程思政教学骨干称号。指导本科生获评“校百篇”优秀论文1篇，院级优秀论文5篇，国家级科创项目3项，大学生国家级学科竞赛三等奖 1项，以第一作者发表中科院1区论文1篇。

六、联系方式

通讯地址：陕西杨凌西农路22号西北农林科技大学食品科学与工程学院

邮政编码：712100

电子邮箱：shanzhongguo@nwafu.edu.cn