王玉堂
作者： 发布日期：2022-10-24 浏览次数：
王玉堂，男，1980年10月生，内蒙古呼和浩特人，九三学社社员，教授，博士生导师，陕西省猕猴桃产业体系岗位专家。
一、主要研究方向
植物源食品功能因子的发掘、体内吸收代谢特征及稳态保持技术的研究。
二、工作学习经历
1999.09-2003.07，内蒙古大学，应用化学专业，本科
2003.09-2008.07，吉林大学，分析化学专业，博士
2008.09-2015.12，西北农林科技大学，食品科学与工程学院，讲师
2014.06-2014.12，台湾清华大学，访问学者
2016.01-2020.12，西北农林科技大学，食品科学与工程学院，副教授
2021.01-至今，西北农林科技大学，食品科学与工程学院，教授
三、代表性学术论文
1. Chang XW, Dong S, Bai WL, Di Y, Gu RJ, Liu FG, Zhao BT, Wang YT*, LiuXB. Methylated metabolites of chicoric acid ameliorate hydrogen peroxide (H2O2)-induced oxidative stress in HepG2 cells. Journal of Agricultural and Food Chemistry , 2021, 69 (7): 2179-2189.
2. Gu RJ, Chang XW, Bai GT, Li X, Di Y, Liu XB, Sun LJ*, Wang YT*. Effects of household cooking methods on changes oftissue structure, phenolicantioxidant capacityand active componentbioaccessibilityof quinoa, Food Chemistry , 2021, 350: 129138-129147.
3. Li X, Dong S, Bai WL, Jia J, Gu RJ, Zhao CC, Liu XB, Wang YT*. Metabolic and transcriptional regulation of phenolic conversion and tocopherol biosynthesis during germination of sesame ( Sesamum indicum L. ) seeds. Food & Function , 2020, 11(11): 9848-9857.
4. Wei L, Zhao C, Dong S, Yao S, Ji B, Zhao B, Liu Z, Liu X, Wang Y*. Secoisolariciresinol diglucoside alleviates hepatic lipid metabolic misalignment involving endoplasmic reticulum-mitochondrial axis. Food & Function , 2020, 11: 3952-3963.
5. Zhao C, Wei L, Yin B, Liu F, Li J, Liu X, Wang J, Wang Y*. Encapsulation of lycopene within oil-in-water nanoemulsions using lactoferrin: Impact of carrier oils on physicochemical stability and bioaccessibility. International Journal of Biological Macromolecules, 2020, 153: 912-920.
6. Li X, Li JY, Dong S, Li YF, Wei LP, Zhao CC, Li JY, Liu XB, Wang YT*. Effects of germination on tocopherol, secoisolarlciresinol diglucoside, cyanogenic glycosides and antioxidant activities in flaxseed ( Linum usitatissimum L. ). International Journal of Food Science and Technology , 2020 54(7): 2346-2354.
7. Diao ZJ, Li J, Liu Q, Wang YT*. In-vivo metabolite profiling of chicoric acid in rat plasma, urine and feces after oral administration using liquid chromatography quadrupole time of flight mass spectrometry. Journal of Chromatography B , 2018, 1081: 8-14.
8. Wang YT, Wen YJ, Ling YC*. Graphene Oxide-Based Magnetic Solid Phase Extraction Combined with High Performance Liquid Chromatography for Determination of Patulin in Apple Juice. Food Anal. Methods , 2017, 10 (1): 210–218.
9. Wang YT, Xie G, Liu Q, Duan X, Liu Z, Liu XB*. Pharmacokinetics, tissue distribution, and plasma protein binding study of chicoric acid by HPLC–MS/MS. Journal of Chromatography B , 2016, 1031: 139–145.
10. Wang YT, Liu LP, Chen L, XiaoCX, Yang P, Liu Q, WangJ, Liu XB*. Rapid determination of trace sulfonamides in milk by graphene oxide based magneticsolid phase extraction coupled with HPLC–MS/MS, Food Analytical Methods , 2016, 9(9): 2521–2530.
11. Wang YT, Liu YY, Xiao CX, Liu LP, Hao M, Wang JG, Liu XB*.Simultaneous Determination of 15 Phenolic Constituents of Chinese Black Rice Wine by HPLC-MS/MS with SPE. Journal of Food Science , 2014, 79(6): 1100–1105.
12. Wang YT, Xiao CX, Guo J, Yuan YH, Wang JG, Liu LP, Yue TL*. Development and application of a method for the analysis of 9 mycotoxins in maize by HPLC-MS/MS. Journal of Food Science , 2013, 78(11): 1752–1756.
13. Wang YT, Liu XB, Xiao CX, Wang ZL, Wang JG, Xiao HF, Cui L, Xiang QS, Yue TL*. HPLC determination of aflatoxin M1 in liquid milk and milk powder using solid phase extraction on OASIS HLB. Food Control , 2012, 28: 131–134.
14. Wang YT, You JY, YuY, Zhang HR, Gao DJ, Ding L, Zhang HQ, Li XW*. Analysis of ginsenosides inpanaxginsenginhighpressure microwave-assisted extraction, Food Chemistry , 2008, 110: 161–167.
15. ZhuD#, WangYT#, DuQW, LiuZG, LiuXB*, Cichoric acid reverses insulin resistance and suppresses inflammatory responses in the glucosamine-induced HepG2 cells, Journal of Agricultural and Food Chemistry , 2015, 63(51): 10903-10913.
16. Liu Q#, Wang YT#, Xiao CX, Wu WQ, Liu X*. Metabolism of chicoric acid by rat liver microsomes and bioactivity comparisons of chicoric acid and its metabolites. Food & Function , 2015, 6(6): 1928-1935.
四、主持的科研项目
[1] 国家自然科学基金面上项目：肠道菌群介导的菊苣低聚果糖对菊苣酸体内转化与生物利用率的影响机制，主持；
[2] 陕西省重点研发计划：功能性彩色马铃薯饮料制备关键技术研究及产品开发，主持；
[3] 国家自然科学基金面上项目：菊苣酸及其代谢产物对体内抗氧化防御酶调节与作用机制研究，主持；
[4] 陕西省重点研发计划：果蔬农药多残留检测关键技术研究与开发，主持；
[5] 中国博士后基金特别资助：菊苣酸/乳铁蛋白体内递送体系构建及脑神经保护作用，主持；
[6] 中国博士后基金面上项目（一等）资助：菊苣酸代谢转化及对脂肪细胞脂解调控机制研究，主持；
[7] 陕西省博士后基金项目（一等）资助：菊苣酸调控体内抗氧化防御酶系统的分子机制研究，主持；
[8] “十二五”国家科技支撑计划子课题：天然食品素材中活性成分提取分离鉴定研究，主持；
[9] 国家科技部重大项目子课题：水果类产品加工原料中真菌毒素检测方法研究，主持；
[10] 教育部中央高校基本科研业务费：牛奶中黄曲霉毒素M1紫外线辐照降解分子机制研究及产物毒性评价，主持；
[11] 西北农林科技大学大型仪器设备新功能开发项目：制备型高效液相色谱-蒸发光散射检测器联用技术研究，主持；
[12] 西北农林科技大学博士启动基金：微波辅助提取技术在食品活性成分提取中的应用，主持。
五、从事的教学工作
承担本科生《食品化学》、《食品分析与检验》，研究生《食品现代分析技术》等课程的教学工作。
六、联系方式
通讯地址：陕西杨凌西农路22号西北农林科技大学食品学院
邮政编码：712100
