彭晓丽,女,教授,博士,博士生导师。教育部学位评审专家、国研评审中心评审专家、国家自然基金同行评审专家,陕西食品产学研协同创新战略联盟副秘书长,现代食品科技、核农学报、International Journal of Biological Macromolecules、Food Function、Journal of Agricultural and Food Chemistry、Food and Chemical Toxicology等中外期刊审稿专家。
一、学习及研修经历
2022.11-2023.12,新加坡国立大学,医学院,国家公派访问学者;
2010.7-今,西北农林科技大学,食品科学与工程学院,讲师/副教授/教授;
2007.9-2010.6,中国农业大学,食品科学与营养工程学院,工学博士;
2004.9-2007.6,西北农林科技大学,园艺学院,农学硕士;
2000.9-2004.6,西北农林科技大学,园艺学院,农学学士
三、科研工作
(一)研究方向
(1)食品营养,包括食品营养因子对糖尿病并发症(肾病、肝部、胰腺病变及功能紊乱)、食品安全危害物损伤机体的营养干预研究;
(2)食品分子毒理,包括食品安全危害因子在实验动物、细胞水平对肠道菌群、细胞损失、线粒体功能、蛋白组/表达谱、信号转导、自噬、氧化胁迫等方面的影响;
(3)果蔬清洗剂研发、功能食品开发。
(二)主持项目
(1)国家自然科学基金面上项目(31571928),60万;
(2)国家自然科学基金青年项目(31201286),23万;
(3)陕西重点研发项目(2020NY-106),10万;
(4)宁夏回族自治区重点研发计划(2023BEG03036),18万;
(5)北京食品营养与人类健康高精尖创新中心开放基金,20万;
(6)中国食品风味与营养健康创新中心开放课题,5万;
(7)西北农林科技大学基本科研业务费青年培育专项基金,4万;
(8)西北农林科技大学基本科研业务费,10万;
(9)西北农林科技大学博士科研启动基金,5万
(10)企业横向项目,5万;
(11)企业横向项目,10万;
(12)企业横向项目,30万;
(13)企业横向项目,5万;
(14)企业横向项目,10万;
(三)发表论文(*通讯作者,#第一作者)
(1) Peng Xiaoli*, Preparation, stability, and in vitro transport of soybean protein-based diosgenin nanoemulsions, Food Chemistry: X, 2023, 20: 100982-100990;
(2) Xiaoli Peng*, Diosgenin inhibits ROS generation by modulating NOX4 and mitochondrial respiratory chain and suppresses apoptosis in diabetic nephropathy, Nutrients, 2023, 15;
(3) Xiaoli Peng*, Diosgenin Targets CaMKK2 to Alleviate Type II Diabetic Nephropathy through Improving Autophagy, Mitophagy and Mitochondrial Dynamics, Nutrients, 2023, 15: 3554-3571;
(4) Boon Wee Teo, Peng Xiaoli, Micromutrients and kidney health, Ann Acad Med Singap, 2023, 52: 386-387;
(5) Xiaoli Peng*, Recent advances and potentiality of postbiotics in the food industry: composition, inactivation methods, current applications in metabolic syndrome, and future trents, Critical Reviews in Food Science and Nutrition, 2022;
(6) Xiaoli Peng*, Diosgenin ameliorated type II diabetes-associated nonalcoholic fatty liver disease through inhibiting de novo lipogenesis and improving fatty acid oxidation and mitochondrial function in rats, Nutrients, 2022, 14, 4994-5010;
(7) Xiaoli Peng*, Linarin ameliorates dextran sulfate sodium-induced colitis in C57BL/6J mice via the improvement of intestinal barrier, suppression of inflammatory responses and modulation of gut microbiota, Food Function, 2022, 13: 10574-10586;
(8) Xiaoli Peng*, Dioscin relieves diabetic nephropathy via suppressing oxidative stress and apoptosis, and improving mitochondrial quality and quantity control, Food Function, 2022,13: 3660-3673;
(9) Xiaoli Peng*, Autophagy and mitochondrial dynamics contribute to the protective effect of diosgenin againse 3-MCPD induced kidney injury, Chemico-Biological Interactions, 2022, 355: 109850-109858;
(10) Xiaoli Peng*,Orally administered diosgenin alleviates colitis in mice induced by dextran sulfate sodium via gut microbiota modulation and short chain fatty acids generation, Journal of Medcinal Food , 2022, 25: 261-271;
(11) Xiaoli Peng*, Nephrotoxicity evaluation of 3-MCPD exposure in Sprague-Dawley rats using Data-Independent Acquisition-Based Quantitative Proteomics analysis, Toxicology Letters, 2021, 356: 110-120;
(12) Xiaolil Peng*, Jujuboside A ameliorates high fat diet and streptozotocin induced diabetic nephropathy via suppressing oxidative stress, apoptosis, and enhancing autophagy, Food and Chemical Toxicology, 2021, 159:112697-112706.
(13) Xiaoli Peng*, LKB1/AMPK alpha signaling pathway and mitochondrial fission/fusion dynamics regulate apoptosis induced by 3-chlorprpane-1,2-diol in HEK293 cells, Food and Chemical Toxicology, 2021, 154: 112350-112358.
(14) Xiaoli Peng*, Diosgenin protects against kidney injury and mitochondrial apoptosis induced by 3-MCPD through the regulation of ER stress, calcium homeostasis and Bcl2 expression, Molecular Nutrition and Food Research, 2021, 65 2001202: 1-11.
(15) Xiaoli Peng*, Inhibition of ER stress attenuates kidney injury and apoptosis induced by 3-MCPD via regulating mitochondrial fission/fusion and Ca2+ homeostasis, Cell Biology and Toxicology, 2021, 5: 1-15;
(16) Xiaoli Peng*, Involvement of NADPH oxidase in patulin-induced oxidative damage and cytotoxicity in HEK293 cells, Food and Chemical Toxicology, 2021, 150: 112055-112064;
(17) Xiaoli Peng*, Apocynin attenuates patulin-induced cytotoxicity through reduction of oxidation stress and apoptosis in HEK293 cells, World Mycotoxin Journal, 2021, 14 (1): 1-10;
(18) Xiaoli Peng*, Drp1-mediated mitochondrial fission induced autophagy attenuates cell apoptosis caused by 3-MCPD in HEK293 cells, Food and Chemical Toxicology , 2020, 145: 111740-111751;
(19) Xiaoli Peng*, Data Independent Acquisition-Based Quantitative Proteomic Analysis Reveals the Protection Effect of Apigenin on Palmitate Induced Lipotoxicity in HAEC cells, Journal of Agricultural and Food Chemistry, 2020;
(20) Xiaoli Peng*, The enoprotective effect of diosgenin on aristolochic acid I-induced renal injury in rats: impact on apoptosis, mitochondrial dynamics and autophagy, Food Function, 2020, 11: 7456-7467;
(21) Xiaoli Peng*, Characterization of oxacillin-susceptible mecA-positive Staphylococcus aureus from food poisoning outbreaks and retail foods in China, Foodborne Pathogens and Disease, 2020,17: 828-735;
(22) Xiaoli Peng*, Transcriptomic and proteomic analysis reveals mechanisms of patulin-induced cell toxicity in human embryonic kidney cells, Toxins, 2020, 12, 681:1-13;
(23) Xiaoli Peng*, Glutathione reduction of patulin-evoked cytotoxicity in HEK293 cells by the prevention of oxidative damage and the mitochondrial apoptotic pathway, Journal of Agricultural and Food Chemistry, 2018, 66: 7775-7783.
(24) Xiaoli Peng*, Protective effects of apigenin against 3-MCPD-induced renal injury in rat, Chemico-Biological Interaction, 2018, 296, 9-17.
(25) Xiaoli Peng*, Apigenin attenuates patulin-induced apoptosis in HEK293 cells by modulation ROS-mediated mitochondrial dysfunction and caspase signal pathway, Toxicon, 2017, 137: 106-113.
(26) Xiaoli Peng#, 3-Monochloro-1, 2-propanediol (3-MCPD) induces apoptosis via mitochondrial oxidative phosphorylation system impairment and the caspase cascade pathway, Toxicology, 2016, 372: 1-11.
(27) Baigang Zhang#, Xiaoli Peng#, Oxidative stress is involved in Patulin induced apoptosis in HEK293 cells, Toxicon, 2015, 94: 1-7.
(28) Xiaoli Peng#,Influence of allicin on quality and volatile compounds of fresh-cut stem lettuce during cold storage, LWT-Food Science and Technology , 2015, 60: 300-307. IF="6.056;
(29) Xiaoli Peng#, Allicin inhibits microbial growth and oxidative browning of fresh-cut lettuce (Lactuca sativa) during refrigerated storage. Food and Bioprocess Technology, 2014, 7: 1597-1605.
(30) Yan Wang#, Xiaoli Peng#, Transcript and protein profiling analysis of OTA-induced cell death reveals the regulation of the toxicity response process in Arabidopsis thaliana. Journal of Experimental Botany, 2012, 63 (5): 2171-2187.
(31) Xiaoli Peng#,Mycotoxin ochratoxin A-induced cell death and changes in oxidative metabolism of Arabidopsis thaliana. Plant Cell Report, 2010, 29: 153-161.
(32) Xiaoli Peng#,Physiological and biochemical responses of grapefruit seed extract dip on ‘Redglobe’ grape. LWT-Food Science and technology, 2009, 42:471-476;
(33) 彭晓丽*,芹菜素对3-氯-1,2-丙二醇诱导的大鼠肾损伤及线粒体分裂融合的影响,食品科学,2018,5(15)(EI);
(34) 彭晓丽*,基因表达谱技术分析棒曲霉毒素肾细胞毒性的机制,现代食品科技,2017,33,6:38-44.
(四)专利
(1)彭晓丽,钟玉杰,罗瑞琳,酸枣仁皂苷B在制备预防/治疗糖尿病肾病的药物中的应用,CN202211242158;
(2)季艳伟,陈利莉,王莹莹,王建龙,王妍入,彭晓丽,吴昊芬,刘源,张开惠,一种金黄色葡萄球菌肠毒素A纳米抗体、应用及试剂盒,CN202110558555.8.
三、教育教学工作
(一)任课课程
工作中先后承担了《免疫学基础》、《食品安全风险评估》、《食品安全保藏学》、《食品卫生学》、《食品分子生物学进展》、《食品质量分析与控制教学实习1》和《食品质量分析与控制教学实习2》等课程的教学和实习的工作。
(二)出版教材
(1)主编《食品免疫学》,ISBN978-7-5184-3827-3,中国轻工社“十四五”规划教材,高校食品营养与健康新专业系列教材;
(2)参编《食品毒理学》,ISBN 978-7-5184-2274-6,中国轻工业出版社十三五规划教材
(三)教改项目
(1)《免疫学基础》教学改革与实践,校级教改,主持;
(2)“金课”视域下《食品免疫学》“六步闭环备课法”的探索和实施,校级教改,参与;
(3)基于OBE教学理念的《食品安全管理和应用综合实践》实习教学改革,校级教改,参与;
(4)食品毒理学教学改革与实践,校级教改,参与
(四)教改论文
(1)彭晓丽#,夏效东,张强,食品免疫学实验课改革的思考,教育教学论坛,2014,51:245-246;
(2)彭晓丽#,张强,夏效东,食品营养与安全专业《食品免疫学》教学体会与思考,中外食品工业,2013:63-65;
(3)季艳伟,彭晓丽,食品免疫学多元化教学模式探索,教育现代化,2021,101:5-11;
(4)季艳伟,彭晓丽*,张道宏,王妍入,王建龙,“金课”视域下食品免疫学教学“六步闭环备课法”探索,中国免疫学杂志,2022
(五)人才培养
(1)独立培养博士生2名,硕士生19名,指导本科毕业论文22名;
(2)指导研究生获奖:国家奖学金1项,金龙鱼奖学金2项,优秀研究生3项;
(3)指导大学生科创项目16项,含国家级1项,省级6项,校级9项,结题优秀4项;
(4)指导大学生学生竞赛获奖7项,包括国家级二等奖1项,三等奖2项,省级一等奖1项,二等奖1项,三等奖1项,校级二等奖1项;
(5)指导本科生以第一作者发表SCI论文2篇,指导本科毕业论文优秀率45%。
四、获奖情况
2022年学院“本科教学先进个人”;
2021年学院“先进工作者”;
2019年春学院“课程思政”讲课比赛三等奖;
2019年秋学院“课程思政”讲课比赛三等奖;
2020年全国大学生生命科学创新创业大赛指导教师三等奖
五、联系方式
通讯地址:陕西省杨凌区西农路22号西北农林科技大学食品科学与工程学院
邮编:712100 联系电话:15319729682 Email:xiaolipeng@nwafu.edu.cn