王玉堂
作者： 发布日期：2026-06-12 浏览次数：
王玉堂，男，1980年10月生，内蒙古呼和浩特人，九三学社社员，教授，博士生导师，陕西省猕猴桃产业体系岗位专家。
一、主要研究方向
植物源食品功能因子的发掘、体内吸收代谢特征及稳态保持技术的研究。
二、学习工作经历
1999.09-2003.07，内蒙古大学，应用化学专业，本科
2003.09-2008.07，吉林大学，分析化学专业，博士
2008.09-2015.12，西北农林科技大学，食品科学与工程学院，讲师
2014.06-2014.12，台湾清华大学，访问学者
2016.01-2020.12，西北农林科技大学，食品科学与工程学院，副教授
2021.01-至今，西北农林科技大学，食品科学与工程学院，教授
三、代表性学术论文
1. Song Y, Zhang Y, Di Y, Li N, Zhao Z, Liu Z, Sun L, Liu X, Wang Y*. Chicoric Acid Differentially Ameliorates Circadian Rhythm Disorder-Induced Liver Glucose Homeostasis Dysregulation in Mice Depending on Intervention Time. Journal of Agricultural and Food Chemistry, 2025, 73(25): 15596-15609.
2. Ji M, Zhang Y, Yu J, Li N, Hou C, Zhang W, Wang Y*. Bioactivity and probiotic potential of bound polyphenols in insoluble and soluble dietary fibers from mango peel during in vitro digestion and fecal fermentation. Food Chemistry, 2025, 492: 145536.
3. Hou C, Chen Y, Zhang W, Yu J, Ji M, Cai S, Wang Y*. An insight into the full aspects of bound polyphenols in dietary fiber: Interaction, composition, function and foundation as well as alteration in food processing. Food Chemistry, 2025, 485: 144553.
4. Hou C, Yu J, Ji M, Chen Y, Liu C, Zhang W, Wang Y*. The study of functional properties of kiwifruit peel dietary fiber and the bioactivity as well as synergetic prebiotic effects of bound phenolics in it during in vitro gastrointestinal digestion and colonic fermentation. Food Chemistry, 2025, 503: 147772.
5. Ye J, Shi R, Wu X, Fan H, Zhao Y, Hu X, Wang L, Bo X, Li D, Ge Y, Wang D, Xia B, Zhao Z, Xiao C, Zhao B, Wang Y*, Liu* X. Stevioside mitigates metabolic dysregulation in offspring induced by maternal high-fat diet: the role of gut microbiota-driven thermogenesis. Gut Microbes, 2025, 17(1): 2452241.
6. Ye J, Shi R, Fan H, Wang D, Xiao C, Yang T, Ye P, Xia B, Zhao B, Wang Y*, Liu X*. Stevioside Ameliorates Prenatal Obesity Induced Postpartum Depression: The Potential Role of Gut Barrier Homeostasis. Molecular Nutrition & Food Research, 2024, 68: 2300255.
7. Hou C, Zhao L, Ji M, Yu J, Di Y, Liu Q, Zhang Z, Sun L, Liu X, Wang Y*. Liberated bioactive bound phenolics during in vitro gastrointestinal digestion and colonic fermentation boost the prebiotic effects of triticale insoluble dietary fiber. Food Chemistry, 2024, 457: 140124.
8. Di Y, Song Y, Xu K, Wang Q, Zhang L, Liu Q, Zhang* M, Liu X*, Wang Y*. Chicoric acid alleviates colitis via targeting the gut microbiota accompanied by maintaining intestinal barrier integrity and inhibiting inflammatory responses. Journal of Agricultural and Food Chemistry, 2024, 72(12): 6276-6288.
9. Chang X, Dong S, Bai W, Di Y, Gu R, Liu F, Zhao B, Wang Y*, LiuXB. Methylated metabolites of chicoric acid ameliorate hydrogen peroxide (H2O2)-induced oxidative stress in HepG2 cells. Journal of Agricultural and Food Chemistry, 2021, 69 (7): 2179-2189.
10. Gu R, Chang X, Bai G, Li X, Di Y, Liu X, Sun L*, Wang Y*. Effects of household cooking methods on changes oftissue structure, phenolicantioxidant capacityand active componentbioaccessibilityof quinoa, Food Chemistry, 2021, 350: 129138-129147.
11. Li X, Dong S, Bai W, Jia J, Gu R, Zhao C, Liu X, Wang Y*. Metabolic and transcriptional regulation of phenolic conversion and tocopherol biosynthesis during germination of sesame ( Sesamum indicum L. ) seeds. Food & Function , 2020, 11(11): 9848-9857.
12. Wei L, Zhao C, Dong S, Yao S, Ji B, Zhao B, Liu Z, Liu X, Wang Y*. Secoisolariciresinol Diglucoside Alleviates Hepatic Lipid Metabolic Misalignment Involving Endoplasmic Reticulum-Mitochondrial Axis. Food & Function, 2020, 11: 3952-3963.
13. Zhao C, Wei L, Yin B, Liu F, Li J, Liu X, Wang J, Wang Y*. Encapsulation of lycopene within oil-in-water nanoemulsions using lactoferrin: Impact of carrier oils on physicochemical stability and bioaccessibility. International Journal of Biological Macromolecules, 2020, 153: 912-920.
14. Wang Y, Diao Z, Li J, Ren B, Zhu D, Liu Q, Liu Z, Liu X*. Chicoric acid supplementation ameliorates cognitive impairment induced by oxidative stress via promotion of antioxidant defense system. RSC Advances, 2017, 7: 36149–36162.
15. Wang Y, Wen Y, Ling Y*. Graphene Oxide-Based Magnetic Solid Phase Extraction Combined with High Performance Liquid Chromatography for Determination of Patulin in Apple Juice. Food Anal. Methods, 2017, 10 (1): 210–218.
16. Wang Y, Xie G, Liu Q, Duan X, Liu Z, Liu X*. Pharmacokinetics, tissue distribution, and plasma protein binding study of chicoric acid by HPLC–MS/MS. Journal of Chromatography B, 2016, 1031: 139–145.
17. Wang Y, Liu L, Chen L, Xiao C, Yang P, Liu Q, Wang J, Liu X*. Rapid determination of trace sulfonamides in milk by graphene oxide based magneticsolid phase extraction coupled with HPLC–MS/MS, Food Analytical Methods, 2016, 9(9): 2521–2530.
18. Wang Y, Liu Y, Xiao C, Liu L, Hao M, Wang J, Liu X*. Simultaneous Determination of 15 Phenolic Constituents of Chinese Black Rice Wine by HPLC-MS/MS with SPE. Journal of Food Science, 2014, 79(6): 1100–1105.
19. Wang Y, Xiao C, Guo J, Yuan Y, Wang J, Liu L, Yue T*. Development and application of a method for the analysis of 9 mycotoxins in maize by HPLC-MS/MS. Journal of Food Science, 2013, 78(11): 1752–1756.
20. Wang Y, Liu X, Xiao C, Wang Z, Wang J, Xiao H, Cui L, Xiang Q, Yue T*. HPLC determination of aflatoxin M1 in liquid milk and milk powder using solid phase extraction on OASIS HLB. Food Control, 2012, 28: 131–134.
21. Wang Y, You J, Yu Y, Zhang H, Gao D, Ding L, Zhang H, Li X. Analysis of ginsenosides in panax ginseng in high pressure microwave-assisted extraction, Food chemistry, 2008, 110: 161–167.
22. Zhu D#, Wang Y#, Du Q, Liu Z, Liu* X, Cichoric acid reverses insulin resistance and suppresses inflammatory responses in the glucosamine-induced HepG2 cells, Journal of Agricultural and Food Chemistry, 2015, 63(51): 10903-10913.
23. Liu Q#, Wang Y#, Xiao C, Wu W, Liu X*. Metabolism of chicoric acid by rat liver microsomes and bioactivity comparisons of chicoric acid and its metabolites. Food & Function, 2015, 6(6): 1928-1935.
四、主持科研项目
1. 国家重点研发计划课题：特种谷物对脑健康调控作用研究及产品创制，主持；
2. 国家重点研发计划子课题：低GI主食食品精准创制关键新技术研发与产业化示范，主持；
3. 陕西省重点研发计划：小麦麸皮高活性膳食纤维功能解析及益生元产品开发，主持；
4. 国家自然科学基金面上项目：肠道菌群介导的菊苣低聚果糖对菊苣酸体内转化与生物利用率的影响机制，主持；
5. 陕西省重点研发计划：功能性彩色马铃薯饮料制备关键技术研究及产品开发，主持；
6. 国家自然科学基金面上项目：菊苣酸及其代谢产物对体内抗氧化防御酶调节与作用机制研究，主持；
7. 陕西省重点研发计划：果蔬农药多残留检测关键技术研究与开发，主持；
8. 中国博士后基金特别资助：菊苣酸/乳铁蛋白体内递送体系构建及脑神经保护作用，主持；
9. 中国博士后基金面上项目（一等）资助：菊苣酸代谢转化及对脂肪细胞脂解调控机制研究，主持；
10. 陕西省博士后基金项目（一等）资助：菊苣酸调控体内抗氧化防御酶系统的分子机制研究，主持；
11. “十二五”国家科技支撑计划子课题：天然食品素材中活性成分提取分离鉴定研究，主持；
12. 国家科技部重大项目子课题：水果类产品加工原料中真菌毒素快速检测，主持；
13. 教育部中央高校基本科研业务费：牛奶中黄曲霉毒素M1紫外线辐照降解分子机制研究及产物毒性评价，主持；
14. 西北农林科技大学大型仪器设备新功能开发项目：制备型高效液相色谱-蒸发光散射检测器联用技术研究，主持；
15. 西北农林科技大学博士启动基金：微波辅助提取技术在食品活性成分提取中的应用，主持。
五、承担教学工作
讲授本科生《食品化学》、《食品仪器分析》和《食品分析与检验》，研究生《高级食品化学》等教学工作。
六、联系方式
通讯地址：陕西省杨凌示范区西农路22号西北农林科技大学食品科学与工程学院
邮政编码：712100
